Publications

2021

Zoledronate Bound to Ceramics Increases Ectopic Bone Volume Induced by rhBMP6 Delivered in Autologous Blood Coagulum in Rats
Nikola Stokovic, Natalia Ivanjko, Igor Erjavec, Anita Breski, Mihaela Peric, Slobodan Vukicevic
Biomedicines
doi: 10.3390/biomedicines9101487
Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies
Nikola Stokovic, Natalia Ivanjko, Drazen Maticic, Frank P. Luyten, Slobodan Vukicevic
Materials
doi: 10.3390/ma14133513
A novel autologous bone graft substitute containing rhBMP6 in autologous blood coagulum with synthetic ceramics for reconstruction of a large humerus segmental gunshot defect in a dog: The first veterinary patient to receive a novel osteoinductive therapy
Pecin M, Stokovic, N, Ivanjko N, Smajlovic A, Kreszinger M, Capak H, Vrbanac Z, Oppermann H, Maticic D, Vukicevic S.
Bone Reports
doi: 10.1016/j.bonr.2021.100759
Synthetic ceramic macroporous blocks as a scaffold in ectopic bone formation induced by recombinant human bone morphogenetic protein 6 within autologous blood coagulum in rats
Stokovic N, Ivanjko N, Milesevic M, Matic Jelic I, Bakic K, Rumenovic V, Oppermann H, Shimp L, Sampath TK, Pecina M, Vukicevic S.
International Orthopaedics
doi: 10.1007/s00264-020-04847-9

2020

Bone morphogenetic proteins: From discovery to development of a novel autologous bone graft substitute consisting of recombinant human BMP6 delivered in autologous blood coagulum carrier
Vukicevic S, Peric M, Oppermann H, Stokovic N, Ivanjko N, Erjavec I, Kufner V, Vnuk D, Bubic-Spoljar J, Pecin M, Novak R, Matic Jelic I, Bakic K, Milesevic M, Rumenovic V, Popek I, Pehar S, Martinovic S, Blazevic V, Rogina L, Vikic-Topic S, Bozic T, Verbanac D, Bordukalo Niksic T, Sampath TK, Pecina M, Maticic D, Grgurevic L
RAD CASA Medical Science
doi: https://dx.doi.org/10.21857/mnlqgc5vgy
Biology of bone morphogenetic protein in bone repair and regeneration: A role for autologous blood coagulum as carrier
Sampath TK, Vukicevic S
Bone
doi: 10.1016/j.bone.2020.115602
Evaluation of synthetic ceramics as compression resistant matrix to promote osteogenesis of autologous blood coagulum containing recombinant human bone morphogenetic protein 6 in rabbit posterolateral lumbar fusion model
Štoković N, Ivanjko N, Pećin M, Erjavec I, Karlović S, Smajlović A, Capak H, Milošević M, Bubić Špoljar J, Vnuk D, Matičić D, Oppermann H, Sampath TK, Vukičević S
Bone
doi: 10.1016/j.bone.2020.115544
A novel autologous bone graft substitute comprised of rhBMP6 blood coagulum as carrier tested in a randomized and controlled Phase I trial in patients with distal radial fractures
Durdevic D, Vlahovic T, Pehar S, Miklic D, Oppermann H, Bordukalo-Niksic T, Gavrankapetanovic I, Jamakosmanovic M, Milosevic M, Martinovic S, Sampath TK, Peric M, Grgurevic L, Vukicevic S
Bone
doi: 10.1016/j.bone.2020.115551
Synthetic ceramic macroporous blocks as a scaffold in ectopic bone formation induced by recombinant human bone morphogenetic protein 6 within autologous blood coagulum in rats
Stokovic N, Ivanjko N, Milesevic M, Matic Jelic I, Bakic K, Rumenovic V, Oppermann H, Shimp L, Sampath TK, Pecina M, Vukicevic S
Int Orthop
doi: 10.1007/s00264-020-04847-9
Autologous blood coagulum containing rhBMP6 induces new bone formation to promote anterior lumbar interbody fusion (ALIF) and posterolateral lumbar fusion (PLF) of spine in sheep
Grgurevic L, Erjavec I, Gupta M, Pecin M, Bordukalo-Niksic T, Stokovic N, Vnuk D, Farkas V, Capak H, Milosevic M, Bubic Spoljar J, Peric M, Vuckovic M, Maticic D, Windhager R, Oppermann H, Sampath TK, Vukicevic S
Bone
doi: 10.1016/j.bone.2020.115448
Autologous bone graft substitute containing rhBMP6 within autologous blood coagulum and synthetic ceramics of different particle size determines the quantity and structural pattern of bone formed in a rat subcutaneous assay
Stokovic N, Ivanjko N, Erjavec I, Milosevic M, Oppermann H, Shimp L, Sampath KT, Vukicevic S
Bone
doi: 10.1016/j.bone.2020.115654
Recombinant Human BMP6 Applied Within Autologous Blood Coagulum Accelerates Bone Healing: Randomized Controlled Trial in High Tibial Osteotomy Patients
Chiari C, Grgurevic L, Bordukalo‐Niksic T, Oppermann H, Valentinitsch A, Nemecek E, Staats K, Schreiner M, Trost C, Kolb A, Kainberger F, Pehar S, Milosevic M, Martinovic S, Peric M, Sampath KT, Vukicevic S, Windhager R
J Bone Miner Res
doi: 10.1002/jbmr.4107

2019

Autologous blood coagulum is a physiological carrier for BMP6 to induce new bone formation and promote posterolateral lumbar spine fusion in rabbits
Vukicevic S, Grgurevic L, Erjavec I, Pecin M, Bordukalo-Niksic T, Stokovic N, Lipar M, Capak H, Maticic D, Windhager R, Sampath TK, Gupta M
J Tissue Eng Regen Med
doi: https://doi.org/10.1002/term.2981

2018

MolPharm/CABS 2018: BMPs and bone repair; Clinical trials in degenerative disc disease
Slobodan Vukicevic, Lovorka Grgurevic
Journal of Bone Oncology
doi: doi.org/10.1016/j.jbo.2018.07.009
Recombinant human bone morphogenetic protein 6 delivered within autologous blood coagulum restores critical size segmental defects of ulna in rabbits.
Grgurevic L, Pecin M, Erjavec I, Capag H, Pauk M, Kufner V, Lipar M, Bubic Spoljar J, Bordukalo-Niksic T, Maticic D, Oppermann H, Peric M, Sampath TK, Vukicevic S.
Journal of Bone and Mineral Research Plus
doi: doi: 10.1002/jbm4.10085
Bone morphogenetic proteins in fracture repair
Dumic-Cule I, Peric M, Kucko L, Grgurevic L, Pecina M, Vukicevic S.
Int Orthop. 2018
doi: doi: 10.1007/s00264-018-4153-y